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Edexcel IGCSE Biology · Spec 2.10-2.13

Enzymes

How enzymes work using the lock-and-key model, enzyme specificity, and the effect of temperature and pH on activity.

Biology revision video

Enzymes

Spec 2.10-2.13

What you need to know

  • Explain how enzymes work as biological catalysts
  • Describe the effect of temperature on enzymes
  • Describe the effect of pH on enzymes

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Quick check

Answer each question before opening the answer.

What is an enzyme and how does the 'lock and key' model work?

A protein that acts as a biological catalyst. The substrate fits the specific active site (like a key in a lock), forming an enzyme-substrate complex.

What happens to an enzyme at high temperature?

It denatures — the active site changes shape so the substrate no longer fits and the reaction stops.

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